Increased albumin excretion in diabetes.

نویسنده

  • J C Townsend
چکیده

In 1964 Keen and Chlouverakis used a radioimmunoassay to measure the concentration of albumin in the urine of diabetic subjects.' Although the urine samples were negative for protein by standard clinical tests, the rate of albumin excretion in the study group was greater than in normal controls. Many studies and review articles have subsequently addressed the clinical implications and pathophysiological mechanisms of these findings. There has been little attempt, however, to assess the consequences of these activities on pathology services. The aim of this review is to give an historical perspective to the main clinical developments of what is often called "microalbuminuria", outline the various analytical methods available, discuss some of the technical difficulties, and consider how pathologists may best provide a worthwhile service to clinicians.

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عنوان ژورنال:
  • Journal of clinical pathology

دوره 43 1  شماره 

صفحات  -

تاریخ انتشار 1990